用于单个生物分子分析的纳米操作和纳米测量技术

The technique of nano-manipulation and nano-measurement for single biomolecule analysis

本文叙述了用于单个生物分子分析的纳米操作和纳米测量技术。光镊子能镊住大分子，按照测量要求进行操作。近场光学扫描显微术是结构生物学的重要研究手段，可以测量大分子的结构。分子马达力学特性测量技术的出现是分子马达研究的新突破，能测出单个分子马达的力学参数。

This paper describes technique of nano-manipulation and nano-measurement for single biomolecule analysis.A large molecule have been brought using a optical tweezer which can move as measurement requirement. The near-field optical scanning microscope is an important.equipment for construral biology, constructure of large molecule is determined using it.It is new breakthrought in molecular reasearch that measure technique o f single of molecular motor mechanics have been developed. Force and displacement on molecular motor moving are measured in nanometer and piconewton scale.