摘要
目的:研究脂肪栓塞综合征血液流变学变化,以及氢化考地松对其影响.方法:实验动物随机分成对照、治疗及未治疗三组.治疗组和未治疗组采用油酸静脉注射诱发脂肪栓塞综合征,治疗组接受氢考治疗.观察三组动物死亡率、纤维蛋白原含量、血小板计数及血液流变学等指标.结果:未治疗组死亡率、纤维蛋白原含量及血粘因素等明显增高,血小板计数明显下降.结论:脂肪栓塞综合征血液多呈高粘滞状态,其原因与纤维蛋白原含量增高及血小板聚集有关.氢考可降低其血液粘滞度.
Aim:Tostudychangesofhemorrheologyinfatembolismsyndrome(FES)andtheefectofhydrocortisoneonhemorrheologyinFES.Methods:Theexperimentalrabbitswereselectedanddividedinto3groups:normalcontrol,treatedanduntreated.FESinthetreatedanduntreatedgroupswasinducedbyintravenousoleicacidandthetreatedgroupreceivedhydrocortisonetherepy.Mortalityrate,plateletcounts,fibrinogenconcentrationandhemorrheololgyindexwereobservedinthe3groups.Results:Itwasfoundthatmortalityrate,fibrinogenconcentration,bloodviscosityincreasedsignificantlyandplateletcountsdecreasedinuntreatedrabbits.Conclusion:HyperviscosityinFESisrelatedtobothincreaseoffibrinogenconcentrationandaggregationofplatelet.HydrocortisonecanreducebloodviscosityinFES.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
1996年第S1期32-34,共3页
Chinese Journal of Trauma