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癌基因和抗癌基因与大肠癌细胞凋亡的调控

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摘要 癌基因和抗癌基因不仅调节和控制肿瘤细胞的增殖,分化和转移,而且也调节肿瘤细胞的凋亡,以往即意为程序性死亡,但有人认为凋亡专指阻断因DNA受损细胞的增强而导致死亡,而程序性死亡指发育中部分细胞的退化和消亡。所以与肿瘤关系密切主要是指细胞凋亡。
出处 《中华消化杂志》 CAS CSCD 北大核心 1996年第S1期101-102,共2页 Chinese Journal of Digestion
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参考文献11

  • 1Hamelin R,et al.Association of p53 mutations with short survival in colorectal cancer. Gastroenterology . 1994
  • 2Hsu B,et al.Expression of bcl-2 gene confers multidrug resistance to chemotherapy-induced cell death. Cancer Bulletin . 1994
  • 3Sinicrope FA,et al.bcl-2 and p53 oncoprotein expression during colorectal tumorignesis. Cancer Research . 1995
  • 4Dejong D,et al.Subcellular lacalization of the bcl-2 protein in malignant and normal lymphoid cells. Cancer Research . 1994
  • 5Offerhous GJA.The relationship of DNA ancuploidy to molecular genetic alterations in colorectal carcinoma. Gastroenterology . 1992
  • 6Albanese I.Structural analysis of c-myc in human sporadic colorectal carcinomas. Anticancer Research . 1994
  • 7Lowe SW,et al.p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell . 1993
  • 8Silvestri R,et al.The bcl-2 protein: a prognostic indicator strorgly related to p53 protein in lymph node negative breast cancer patients. Journal of the National Cancer Institute . 1994
  • 9Fearon E,Vogelstein B.A genetic model for colorectal tumorigenesis. Cell . 1990
  • 10Endocott JA,Ling V.The biochemistry of p-glycoprotein mediated multidrug resistance. Annual Review of Biochemistry . 1989

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