鼻咽癌颈部淋巴结转移切取活检对其预后的影响

The influence of cervical cervical incisional biopsy of nasopharyngeal cancer(NPC)on prognosis

目的分析颈部肿物切取活检对鼻咽癌放疗的影响。材料与方法１９８３年２月～１９８６年４月间收治有颈部淋巴结转移的鼻咽癌１０８例，其中经鼻咽部活检者６５例，经颈部切取活检者４３例，全部行根治性放疗。结果鼻咽部活检组３，５年生存率分别为６０．０％及５５．４％；颈部切取活检组３，５年生存率分别为３９．５％及３４．９％。鼻咽活检组５年死亡病例的远处转移率为５９．３％；颈部切取活检组为８５．７％，均具有显著性差异（Ｐ＜０．０５）。结论鼻咽癌颈部淋巴结转移切取活检可增加其远处转移率，降低生存率。

Purpose To analyze influence of cervical incisional biopsy of nasopharyngeal cancer on prognosis Materials and Methods 108 NPC patients with cervical lymph node metastases were treated byradical radiotherapy from February,1980 to April,1986. 65 patients received biopsies in the nasopharyngx and 43 patients received incisional biopsies in the neck nodes.Results The 3～,5～year survival rates were 60. 0%,55. 4% in the group which received nasopharyngeal biopsy but 39.5%and 34.9% in cervical incisional biopsy group.59,3 % and 85.7 % patients died of distant metastasis within 5 years after treatment in above two groups,respectively(P<0.05).Conclusion Cervical incisional biopsy increases distant metastatic rate and decreased survival rate for NPC.