不同线束治疗鼻咽癌颈转移淋巴结的远期疗效比较

Comparison of long-term effects between treatments by 60 Co only and 60 Co combined with deep X-ray irradiation for neck node metastasis of nasopharyngeal carcinoma

目的分析比较鼻咽癌颈转移淋巴结应用６０Ｃｏ与６０Ｃｏ加深部ｘ线治疗的远期疗效。材料与方法１９７７年３月～１９８３年１２月共收治３１０例鼻咽癌，其中有颈淋巴结转移２７６例。分两组治疗，单纯６０Ｃｏ治疗１３４例，６０Ｃｏ合并深部ｘ线治疗１４２例。结果５，１０年生存率单纯６０Ｃｏ组为１７．９％、９．７％，６０Ｃｏ加深部ｘ线组为２８．２％，１９％，两组差异有显著意义（Ｐ＜０．０５）；通过对临床分期及Ｎ病期与５，１０年生存率两组的对比分析，Ⅲ期Ｎ２单纯６０Ｃｏ组明显低于混合线束组（Ｐ＜０．０５）。结论 提示鼻咽癌颈转移淋巴结采用６０Ｃｏ合并深部ｘ线混合线束治疗是有利的，特别是在Ｎ２病人中。

Purpose To compare long-term effects of treatment between 60 Co only and 60 Co combined with deep X-ray irradiation for carcinoma metastatic cervical lymph nodes of NPC,Materials and Methods 275 NPC patients with metastatic cervical lymph nodes were treated from March 1977 to December 1983 Patients were divided into two groups:134 patients received 60 Co only and 142 patients received 60 Co combined with deep X-ray irradiation in the neck.Results The 5-,10-year survival rates were17.9% and 9.7% in the 60 Co group,28.2% and 19% in the 60 Co plus X-ray group .The defference between these two group,was statistically significant(P< 0.05),The 10-year survival rates in the 60 Co group were markediy decteased as compared with those of the 60 Co plus X-ray group of stage Ⅲ patients(P<0.05). Conclusion It is considered that combination of 60 Co and deep X-ray irradiation is favorable in the treatment of cervical lymph node metastasis of NPC,in parucular for N2 patients.