一氧化氮与心血管疾病
摘要
1987年美英两国的学者同时发现血管内皮细胞能产生一氧化氮(No),并证明它即为内皮衍生舒张因子(EDRF)。随着对No研究的深入,发现No是一种新的细胞间信息交换的重要载体,调节内皮细胞、平滑肌和神经等细胞功能,参与炎症与组织细胞损伤和增殖,对全身多系统生理功能与疾病的产生起重要作用。
参考文献25
-
1Moncada S,,Higgs EA,Hodson HF et al.The L-arginine:nitric oxide pathway. Journal of Cardiovascular Pharmacology . 1991
-
2Ahlner 3,Andersson RGG,Torfgard K et al.Organic nitrate esters:clinical use and mechanisms of action. Pharmacology Reviews . 1991
-
3Toda N,Kifamura Y,Okamura T.Neural mechanism of hypertension by nitric oxide synthase inhibitor in dogs. Journal of Hypertension . 1993
-
4Luscher TE,Dohi Y,Tschudi M.Endothelium-dependent regulation of resistance arteries:Alterations with aging and hypertension. Journal of Cardiovascular Pharmacology . 1992
-
5Shepherd JT,Zvonimir S.Endothelium-derived vasoactive factor:I.endothelium dependent relaxation. Journal of Hypertension . 1991
-
6Nakazono K,Watanabe N,Matsuno K et al.Does superoxide underlie the pathogenesis of hypertension?. Proceedings of the National Academy of Sciences of the United States of America . 1991
-
7Henderson AH.Endothelium in control. British Heart Journal . 1991
-
8Harrison DG.Endothalial dysfunction in the coronary microcirculation:A new clinical entity or an experimental finding?. The Journal of Clinical Investigation . 1993
-
9Woolfson RG,Patel VC,Neild GH et al.Inhibition of endothelium-derived nitric oxide reduced infarction size. Circulation . 1992
-
10Fratacci MD,Frostell CG,Chen TY et al.Inhaled nitric oxide,a selective pulmonary vasodilator of heparin-protamine vasoconstriction in sheep. Anesthesiology . 1991
共引文献2
-
1齐顺贞,杨宗城,何保斌,傅琼芳,刘志远,黎鳌.吸入一氧化氮降低吸入性损伤所致肺动脉高压的实验研究[J].解放军医药杂志,1996,18(5):324-326.
-
2张喆颖,任锡玲.内皮素一氧化氮与肝硬变[J].世界华人消化杂志,1996,5(1):40-41. 被引量:9
-
1赵华,张惠荣,卢献灵.一氧化氮及一氧化氮合酶与呼吸系统疾病的关系及临床意义[J].新疆医学,2007,37(4):49-50.
-
2陈冬志,孟明,韩艳梅,凌亦凌.一氧化氮与肺动脉高压[J].河北职工医学院学报,1999,16(3):58-62.
-
3王勇,李兴利,杨力,顾炳权.病毒性肝炎患者血清一氧化氮变化及临床意义[J].吉林医学信息,2008,0(Z1):6-7.
-
4郭明春,李良玉,孟飞燕.卡托普利对冠心病患者血清内皮衍生舒张因子及脂质过氧化物水平的影响[J].中国实用医刊,2009,36(15):80-81.
-
5张召平,李媛,宋文杰.卡托普利对冠心病患者血清内皮衍生舒张因子及脂质过氧化物水平的影响[J].临床军医杂志,2008,36(1):50-51.
-
6卢英民,毛焕元,曹林生.血浆内皮素和内皮衍生舒张因子与先天性心脏病肺动脉高压关系的研究[J].临床心血管病杂志,2003,19(2):93-94. 被引量:5
-
7池萍,林财珠,陈伯銮.内皮素、内皮衍生舒张因子的平衡与高血压及麻醉[J].国外医学(麻醉学与复苏分册),2001,22(1):13-15. 被引量:2
-
8高连如.内皮衍生舒张因子与高血压[J].中国循环杂志,1994,9(8):500-503. 被引量:3
-
9刘树林,顾炳权,杨秋荣.病毒性肝炎患者血清一氧化氮变化及其临床意义[J].第四军医大学学报,2001,22(4). 被引量:6
-
10卢英民,乔守炎,毛焕元.冠心病患者内皮衍生舒张因子与白细胞介素-8的变化及临床意义[J].心肺血管病杂志,1999,18(1):33-34.