摘要
对76例精神分裂症病人(Ⅰ型47例,Ⅱ型29例)进行了血清过氧化酯质(LPO)、水溶性脂质过氧化物(wsFS)、维生素E(VE)、谷胱甘肽过氧化物酶(GPX)的测定,并与50名年龄相似的正常人相比较,发现精神分裂症病人血浴LPO、wsFS含量较正常人显著增高,而VE、GPX均低于正常人,其中Ⅱ型精神分裂症病人血清VE含量又较I型病人低。经氯丙嗪治疗后I型病人血清中上述含量有较大变化,而在Ⅱ型病人则没有明显变化。作者简单分析了自由基与Ⅰ、Ⅱ型精神分裂症的关系。
he authors deternumed the serum LPO, ws-FS, VE. GPX of 76 schizophrenics (including 47 Ischizophrening and 29 II schizophrenics ) and com-pared with those of the 50 normal controls at the similar age. The resuits showed that the content ofserum LPO and wsFS in the schizophrenics were re-markably higher than those in the normal controls,the content of VE and GPX were lower than in thecontrols . and among them the content of the serumVE in II schizophrenics were lower than that in Isehizophrenics . After treating with chlopromazine ,the contents above changed greatly in IIschizophrenics , but not in I schizophrenics. It alsoanalysed the relation between free radical and I, IIschizophrenia.
出处
《中国民康医学》
1996年第6期334-336,共3页
Medical Journal of Chinese People’s Health