大强度训练对自行车运动员淋巴细胞亚群和NK细胞活性的影响

THE EFFECTS OF HIGH-INTENSITY EXERCISE ON T-LYMPHOCYIE SUBSETS AND NATURAL KILLER CELL ACTIVITY IN BICYCLE PLAYER

本文观察了大强度训练对自行车运动员外周血T淋巴细胞亚群和NK细胞活性的影响。实验结果发现,经过四周大强度训练,CD8+细胞比例显著上升(P<0.05),CD4+/CD8+比值显著下降(P<0.05),NK细胞活性显著下降(P<0.05)。提示大强度训练造成机体免疫功能下降与抑制性T淋巴细胞过度激活,继发造成免疫平衡失常和NK细胞活性下降有关。

Purpose of this study was to observe the effects of four weeks high-intensity exercise on T-lymphocyte subsets and natural killer cell activity. Six elite female bicycle players undertook this test. T-lymphocyte subsets was detected by flow cytometry and NKCA was assessed by the LDH release assay. The results showed that after four weeks high- intensity exercise the percentage of CD8+cell was significantly increased, the ration of CD4 + /CD8+ was significantly lower in post-exercise than in preexercise. NKCA was significantly decreased. These results Suggest that high-intensity exercise possibly disturbed immune function and increase the susceptibility to infections.