摘要
Using a combined microsphere retrograde transport with immunofluorescence technique,the glutamate-immunoreactive neurons in the medullary raphe nuclei that project to the cerebellar cortex were investigated in the present study.The cells double-labeled by glutamate-immunoresctivity and microspheres were found in all medullary raphe nuclei.Among all the cerebellar projection neurons in the medullary raphe nuclei,(49. 49±2.78)% (±)in pallidus (NRP),(62.02±3. 62) % in obscures (NRD),(3. 03±3. 03) % in magnus (NRM) were immunoreactive to glutamate.The results raise the possibility that the cerehellar vermal cortex (lobules Ⅴ-Ⅶ) may receive some excitatory input from medullary raphe nuclei to affect the function of the cerebellum.
Using a combined microsphere retrograde transport with immunofluorescence technique,the glutamate-immunoreactive neurons in the medullary raphe nuclei that project to the cerebellar cortex were investigated in the present study.The cells double-labeled by glutamate-immunoresctivity and microspheres were found in all medullary raphe nuclei.Among all the cerebellar projection neurons in the medullary raphe nuclei,(49. 49±2.78)% (±)in pallidus (NRP),(62.02±3. 62) % in obscures (NRD),(3. 03±3. 03) % in magnus (NRM) were immunoreactive to glutamate.The results raise the possibility that the cerehellar vermal cortex (lobules Ⅴ-Ⅶ) may receive some excitatory input from medullary raphe nuclei to affect the function of the cerebellum.
