稀土La^（3＋）对α－石英细胞毒性拮抗作用的研究

Study on Refraining Effect of Rare Earth La￣(3+)To Toxicity of α-quartz cell

本文采用家兔肺泡巨噬细胞（ＡＭ）体外培养法，以细胞存活率、细胞内游离钙离子浓度（［Ｃａ（２＋）］ｉ）为指标，研究了稀土Ｌａ（３＋）对二氧化硅细胞毒性的拮抗作用。结果提示Ｌａ（３＋）可能通过阻断细胞膜的Ｃａ（２＋）内流来达到拮抗石英细胞毒性的作用。

According to the mumber of living cells and cytoplasmic free ca2+ concentration of cells,by means of culturing outside of body for the macrophage in vitro of home rebbits,it has been in vestigated the refraining effect of rare earth La3+ to toxicity of oilica cells,The result reveals that La3+ has effect on refraining possibly to run inside of ca2+ through the cell membrane by cutting off it.