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急性心肌梗塞二级预防的大系列前瞻性随机对照临床试验

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摘要 近年来国际上先后组织了数百个大规模多中心前瞻性临床试验,所获结果因其科学位和普遍性,对临床工作具有重大指导意义。现综述急性心肌梗塞(AMI)二级预防的国际性大系列前瞻性随机化对照临床试验结果如下。1 抗心律失常药物的应用 为了评价用抗心律失常药物抑制AMI后无或轻度症状性室性心律失常能否降低病死率,著名的CAST选用了经CAPS筛选出的药物:高效的恩卡胺(Encainide)、氟卡胺(Flecainide)和中效的乙吗噻嗪(Moricizine)。
作者 吕柏宁
出处 《西南国防医药》 CAS 1996年第6期374-376,共3页 Medical Journal of National Defending Forces in Southwest China
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  • 1Gruppo Itallano per Lo Studio Della Soppavvivenza Nell’Infarto Miocardico.GISSI-2: A factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12490 patients with acute myocardial infarction[].LancetThe.1990
  • 2Gruppo Itallano per Lo Studio Della Soppavvivenza Nell’Infarto Miocardico.GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. The Lancet . 1994
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