摘要
52例肝豆状核变性患者用HLD长期治疗的疗程为10.25±3.84a(5.1~21.4a).总有效率为94.2%,其中9例无症状患者仍未出现肝脑症状,且K-F环消失或变为浅谈.并观察HLD的常见不良反应.
Fifty-two patients with hepatolenticular degeneration (HLD) treated with penicillamine were reported. Mean courses of treatment were 10. 25±3.84 years (5.1 to21. 4 years). After long-term follow-up, the total effective rate was 94. 2%.Nine patients with no symptoms of liver and brain remained asymptomatic, and Kayser-Fleischer rings faded or disappeared. The common adverse reaction of penicillamine and its managements was discussed.
出处
《中国临床药学杂志》
CAS
1996年第2期45-48,共4页
Chinese Journal of Clinical Pharmacy
关键词
肝豆状核变性
青霉胺
不良反应
hepatolenticular degeneration
penicillamine 5 adverse reaction