肾脏疾病患者血清APOA1_1等的测定及其临床意义

本文采用火箭免疫电泳的方法检测了67例肾脏疾病患者血清A_(po)A_1、A_(po)B_(100)及A_1/B_(100)等值,并选择了25例正常人做对照。结果可见(1)急性肾小球肾炎患者血清A_(po)A_1和A_(po)B_(100)浓度均升高,A_1/B_(100)比值正常(P>0.05);(2)慢性肾小球肾炎、慢性肾功衰竭、糖尿病性肾病和肾病综合症患者血清A_(po)A_1降低或和A_(po)B_(100)升高,A_1/B_(100)比值明显低于正常人(P<0.01)。