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DIRECT PREPARATION AND MEIOTIC ANALYSIS OF HUMAN SEMEN

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摘要 A meiotic study of human semen specimens was carried out in 60 cases. Among them, 20 were normal controls, 20 suffered from infertility, and 20 had a history of recurrent spontaneous abortions. Of the cases of infertility and abortion, 50% were found to hare numerical and / or structural chromosomal aberrations in spite of the normal blood karyotype. It is suggested that chromosomal aberrations may be the cause of sterility and abortion. The success rate of semen chromosome G-banding in the infertility, abortion and control groups was 70%, 55% and 25% respectively. The semen samples of three cases of heterozygous carriers with reciprocal chromosomal translocation were also studied. The ring quadrivalents were identified in all cases. The results may explain the recurrent abortions in these patients.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 1995年第5期24-28,共5页 中华医学杂志(英文版)
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参考文献3

  • 1Renee H. Martin,Alfred W. Rademaker,Kathy Hildebrand,Leslie Long-Simpson,Dianna Peterson,Judy Yamamoto. Variation in the frequency and type of sperm chromosomal abnormalities among normal men[J] 1987,Human Genetics(2):108~114
  • 2C. Templado,F. Vidal,J. Navarro,J. Egozcue. Improved technique for the study of meiosis in ejaculate: results of the first 50 consecutive cases[J] 1986,Human Genetics(3):275~277
  • 3J. M. Luciani,M. R. Guichaoua,M. R. Morazzani. Complete pachytene chromomere karyotypes of human spermatocyte bivalents[J] 1984,Human Genetics(2-3):267~271

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