素高捷经纤维支气管镜局部滴入治疗支气管扩张症的近期观察

The Short-term Observation of Bronchiectasis Treatment with Socoseryl via Fibrosic Bronchoscope

本文将1991年4月至1993年10月我所进行经纤维支气管镜滴入素高捷治疗支气管扩张症共21例，并与21例单纯滴入丁胶卡那霉素（或妥布霉素）进行比较。结果显示：（1）治疗组症状改善率为61．8％，高于对照组16.5％。（2）支气管炎症改善率为98．4％，高于对照组18.7％。（3）治疗组总有效率为100％，高于对照组49．4％。

In this article,we compared 21 patients with bronchiectasis treated with Socoseryl via fibrosic bronchoscope vs 21 those treated with antibiotics in our institute from April 1991 to October 1993. The patients in Sacoseryl group received Socoseryl 5ml /per time plus Amikacin 0. 4/pre time (or Tobramycin 160,000 unit/per time), twice a week (average 4. 25 weeks), whereas those in control group only treated with Amikacin 0. 4/per time (or Tobramycin 160,000 unit/per time),twice a week (average 4. 25 weeks ). The observatory period lasted from six months to three years. Results: (1)The rate of symptom improvement in Socoseryl group was 61.8%, higher than those in control group (16. 5% ),p<0.01; (2)Therate of improvement of br0ncheal inflammation in Socoseryl grotlp was 95. 4%,higher than those in control group (18. 7% ), P<0. 01; (3) The overall effective rate of Socoseryl group was 100%, higher than those in control group (49. 4), P<0.01. These results indicated that Socoseryl could be used to cure patients with mild or moderate bronchiectasis.