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血小板生成素的研究进展 被引量:1

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摘要 生成血小板的巨核细胞是从骨髓造血干细胞分化发育来的。造血干细胞首先分化生成巨核系祖细胞,即巨核系集落形成单位。祖细胞阶段的细胞核内的DNA一般是2—8倍体,当祖细胞是2倍体或4倍体时具有增殖能力,这也是巨核细胞系可以增加细胞数量的唯一阶段。巨核系祖细胞继续向前分化成为具有8-32倍体的巨核细胞。
出处 《中国实验血液学杂志》 CAS CSCD 1995年第4期344-347,共4页 Journal of Experimental Hematology
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  • 1Kaushansky K,Lok S,Holly RD,et al.Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature . 1994
  • 2Gewirtz AM.Human megakaryocytopoiesis. Seminars in Hematology . 1986
  • 3Methia N,Louache F,Vainchenker W et al.Oligodeoxynucleotides antisense to the protooncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood . 1993
  • 4Lok S,Kaushansky K,Holly RD,et al.Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature . 1994
  • 5Vigon I,Mornon JP,Cocault L et al.Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proceedings of the National Academy of Sciences of the United States of America . 1992
  • 6de Sauvag,FJ,Hass PE,Spencer SD et-al.Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature . 1994
  • 7Vigon I,Florindo C,Fichelson S et al.Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth. Oncegene . 1993
  • 8Foster DC,Sprecher CA,Grant FJ et al.Human thrombopoietin: gene structure, cDNA sequence,expression, and chromosomal localization. Proceedings of the National Academy of Sciences of the United States of America . 1994
  • 9Wendling F,Maraskovsky E,Debili N et al.c-Mpl ligand is a humoral regulator of megakary-ocytopoiesis. Nature . 1994
  • 10Cowling J,Dexter M.Erythropoietin and myeloid colony stimulating factors. Trends in Biotechnology . 1992

共引文献4

同被引文献6

  • 1石小玉,中国实验血液学杂志,1998年,6卷,11页
  • 2Xi X D,Br J Heamatol,1995年,90卷,921页
  • 3胡志远,中国实验血液学杂志,1995年,3卷,344页
  • 4Han Z C,Int J Hematol,1992年,55卷,281页
  • 5Han Z C,J Lab Clin Med,1992年,120卷,646页
  • 6石小玉,李文林,熊丽霞,关华凤,龙飞,章克萍.重组人血小板生成素对人红白血病HEL细胞增殖的影响[J].中国实验血液学杂志,1998,6(1):11-13. 被引量:1

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