实时三维超声心动图对急性肺栓塞患者右心功能的评估

Evaluation of global right ventricular function in patients with acute pulmonary embolism using Real-time Three-dimensional echocardiography

目的:探讨实时三维超声心动图(RT-3DE)评价急性肺栓塞(APE)患者右心功能的价值。方法:使用RT-3DE采集30例APE患者和30例健康志愿者心脏全容积图像导入TomTec工作站,应用4D RV-Function软件分析,生成右室容积-时间变化曲线(RV-VTC)。比较两组对象RT-3DE参数右室舒张末期容积(EDV)、收缩末期容积(ESV),射血分数(EF),峰值排空率(PER)和峰值充盈率(PFR)之间的差异。结果:与对照组相比,APE患者右室整体EDV、ESV增大,EF、PER、PFR减小,差异均有统计学意义(t=2.490、2.172、2.897、2.894及3.042,均P<0.05)。结论:APE患者的右室整体收缩及舒张功能减低,RT-3DE可以准确评价APE患者右心功能改变。

Objective： To explore the value of the right ventricular（RV） global function in patients with acute pulmonary embolism（APE） by using real-time Three-dimensional echocardiography（RT-3DE）.Methods： 30 normal controls and 30 patients with APE were studied.And all the three-dimensional echocardiographic datasets were acquired.Then series of RV parameters,namely end diastolic volume（EDV）,end systolic volume（ESV）,RV ejection fraction（EF） were offline measured by TomTec 4D RV-Analysis software which can also provide the right ventricular volume-time curves（RV-VTC）.EDV,ESV,EF,RV peak filling rate（PFR） and RV peak ejection rate（PER） from RT-3DE were investigated in the two groups.Results： Compared with control group,the value of EDV and ESV were larger;EF,PER,PFR were reduced,there were significant differences in the two groups（t=2.490,2.172,2.897,2.894 and 3.042,respectively,all P0.05）.Conclusion： The RV function in patients with APE is decreased and RT-3DE can evaluate RV volume and global function accurately.