64例喉癌治疗结果分析

An Analysis of the Treatment of 64 Patients with Laryngeal Carcinoma

对６４例被治喉癌治疗结果进行回顾性分析。治疗方法包括单纯放疗１９例、放疗加化疗１０例、手术后放疗２２例、手术后放疗加化疗１３例。随访率为９５．３％，总的５年生存率为４２．１８％。结果表明：手术后放疗加或不加化疗的生存率都高于其他方法的生存率（Ｐ＜０．００１）；单纯放疗剂量以６０～７５Ｇｙ、术后放疗剂量以５０～６０Ｇｙ为佳；Ⅰ期病人采用单纯放疗的三、五年生存率分别为９０．９％、７２．７％；有颈淋巴结转移的病人预后差。说明早期发现、合理选择治疗方法是提高喉癌生存率的关键。

A retrospective analysis of the treatment of 64 patients with laryngeal carcinoma from1974 to 1988 was made,Nineteen patients were treated with radiotherapy alone,10 with acombination of radiotherapy and chemotherapy,22 with a combination of surgery and radio-therapy and 13 with a combination of surgery and chemotherapy. The follow-up rate was95.3%and 5-year survival rate was 42. 18%. The results showed that the survival rate of pa-tients receiving postoperative radiotherapy with or without chemotherapy was higher thanthat of the others(P<0. 001).60-70 Gy was advised for radiotherapy alone and 50-60 Gy forpost-operative radiotherapy. The 3-year and 5-year survival rate for stage I patients with ra-diotherapy alone were 90.9%and 72.7%respectively. Patients with Iymph-node metastaseshad worse survival. Early finding and reasonable choice of treatment were the key points toimprove the survival rate of laryngeal carcinoma.