摘要
对最常用的非线性药动学模型,静注Michaelis—Menten消除动力学模型,导出了药动学统计矩的计算公式和便于应用的近似公式,误差分析表明,近似公式有较好的精度.
For intravenous injection,formulas are derived in this paper to calculate statistical moments of Michaelis--Menten elimination kinetic model,a commonly used nonlinear pharmacokinetic model.Approximate formulas with high precision are also given to simplify calculation for application.
出处
《生物数学学报》
CSCD
北大核心
1995年第4期180-184,共5页
Journal of Biomathematics
关键词
统计矩
静脉注射
近似计算
药物动力学
Statistical moment
Intravenous injection
Approximate calculation
Pharmacokinetic.