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丙型肝炎病毒感染与原发性肝癌 被引量:3

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摘要 流行病学调查及临床研究证明,原发性肝癌(PHC)的发病除了与乙型肝炎病毒(HBV)、黄曲霉素等因素有关外,且与丙型肝炎病毒(HCV)感染密切有关。本文就HCV感染与PHC的关系作简要介绍。1 HCV抗体检测 自1989年Choo等首先应用分子克隆技术,获得本病的基因克隆,并建立血清HCV检测方法以来,应用C 100-3抗原包被载体,以RIA或EIA法检测抗HCV,作为第一代诊断HCV感染的方法。HCV的确定是近年来肝病研究中最重要的成就。第一代检测法可在约50%急性HC和80%慢性HC中检出抗HCV,但其敏感性较低。因为在抗C
作者 陈士葆
出处 《世界华人消化杂志》 CAS 1994年第4期239-240,共2页 World Chinese Journal of Digestology
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