双原发性肺癌的治疗

TREATMENT RESULTS OF DOUBLE PRIMARY BRONCHOGENIC CARCINOMA

１９５８年～１９９０年我院收治肺癌１０６３３例，发现双原发肺癌３１例，发生率为０．３％。１２例同期发生，１９例非同期发生，间隔时间１～１５年。组织学不同类型１１例，同类型１２例。第一原发癌以手术治疗为主（２６／３１）。第二原发癌手术１２例，放疗１７例，化疗２例。中位生存期手术为１６．５月，放疗为１３月，化疗为９月。３及５年生存率手术组分别为３３％，１３％，放疗组为６％，０％。本文讨论了双原发肺癌的发生率，诊断标准及治疗方法。

AbstractThirty-one cases of double primary bronchogenic carcinoma(12 simultaneousand 19 consecutive) were encountered among 10633 patients treated for bronchogen-ic carcinoma from 1958- 1990. The interval between the appearance of twoprimarytumors ranged from 1 year to 15 years, with a median of 5 years. Most of theprimary lesions underwent resection,The treatment of the second primarycarcinoma in 12 patients were treated by resection,with a median survival of 16.5months; 17 patients were treated by irradiation,with a median survival of 13 monthsand 2 patients were treated by chemotherapy,with a median survival of 9 months. The 3-year and 5-year survival rates were 33%,13%in the resection group and 6%,0%in irradiation one. The incidence, diagnostic criteria and treatment of doubleprimary bronchogenic carcinoma are discussed.