摘要
本文采用体外培养方法就红毛五加茎皮多糖对癌细胞生物学效应及其抗癌机制进行了初探。实验结果证明,红毛五加茎皮多糖具有良好的抗癌效果,能使体外培养的人白血病粒细胞形态明显改变,癌细胞生长受抑制,细胞生长曲线下降,细胞死亡率上升,流式细胞分光光度计测定分析,提示癌细胞合成DNA的前期受到抑制,阻断DNA的合成。
The effects of polyhexose on the K562 cell line were studied and we observed that the cell growth activity was inhibited by polyhexose in cell culture. By using FCM technique it was found that the DNA synthesis of K562 cell line in G1 phase, S phase and G+M phase was inhibited, whereas that of normal cell (embrynate prepuce fibrocyte) was not by polyhexose.
出处
《中国组织化学与细胞化学杂志》
CAS
CSCD
1994年第1期72-75,共4页
Chinese Journal of Histochemistry and Cytochemistry
基金
国家自然科学基金