摘要
本文通过海洛因对30只大白鼠主要病理实验研究,普遍发现组织上皮和细胞增生,各组织不同程度的炎细胞浸润(特别以肝、肺、脑、心、肾、肾上腺、肌肉明显),并有不同程度充血、变性、肺部普遍出现间质性肺炎、脑组织水肿;各组镜下积分以亚急性中毒组积分最高达19.11±3.5分,慢性中毒组为14.92±3.26分,与正常组有非常显著差异P<0.001,与吸烟组亦差异显著P<0.01,说明长期使用海洛因会导致各组织器官改变,以致全身脏器损害。
The effects of heroin on 30 rats in pathomorphology were observed. It was found the extensive hyperplasia of the epethelial cells, imflammatory in filtration at different levels in all tissues, (especially in liver, heart, lungs, brain, kidneys, adrenal glands and muscles); hyperemia and degeneration in some tissues and organs. The rats had interstitial pneumonia and cerebral edema. The intergral value of the subacute toxic group was up to 19.11+3.5 and of the chronic toxic one was 14. 92?. 26. Compared with the normal group and smoking group, the imtergral values of two toxic groups were bigger (P<0.01-0. 001), which indicated that the long-term using of heroin was harmful to tissues and organs of the body.
出处
《西南国防医药》
CAS
1994年第6期332-334,384,共4页
Medical Journal of National Defending Forces in Southwest China
