摘要
DNA adduction with nicotine in mouse liver at environmental doses has been observed using 14C-label by accelerator mass spectrometry(AMS).An improved detection limit of DNA adducts of 1 adduct per 1011 nucleotides has been given. It is primarily proposed that nicotine appears carcinogenic via its conversion to nitrosamines.
DNA adduction with nicotine in mouse liver at environmental doses has been observed using 14C-label by accelerator mass spectrometry(AMS).An improved detection limit of DNA adducts of 1 adduct per 1011 nucleotides has been given. It is primarily proposed that nicotine appears carcinogenic via its conversion to nitrosamines.