摘要
N-Bromomethyl-N-methyl- 1,2, 3,4-tetrahydro-iso-quinolinium bromide(1)reacted with sodium 2, 6-di-tert-butylphenoxide to afford compound 2a. 3a. 4 and 5 via the benzylic N-ylide intermediate. Meanwhile, when compound 1 reacted with tri-n-butylphosphine the coupling compound 7 was obtained via demethylation reaction. The reaction mechanisms were discussed.
N-Bromomethyl-N-methyl- 1,2, 3,4-tetrahydro-iso-quinolinium bromide(1)reacted with sodium 2, 6-di-tert-butylphenoxide to afford compound 2a. 3a. 4 and 5 via the benzylic N-ylide intermediate. Meanwhile, when compound 1 reacted with tri-n-butylphosphine the coupling compound 7 was obtained via demethylation reaction. The reaction mechanisms were discussed.
基金
the financial support of Chinese Natural Science Foundation.
