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Fluorescence study on the coaggregating tendencies of the cholesterols --the culprits of arteriosclerosis

Fluorescence study on the coaggregating tendencies of the cholesterols --the culprits of arteriosclerosis
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摘要 The coaggregating tendencies of the culprits of arteriosclerosis, the cholesteryl esters (CE-n's), have been investigated in the 40:60 V/V (Φ= 0.40) dioxane (DX)-H2O system, by using decyl pyrenyl ketone (Py-11) as the fluorescence probe. The fluorescence intensity of Py-11 decreases when coaggregation occurs between CE-n and Py-11, because of the low polarity of the microenviroment of the coaggregates. The order of the coaggregating tendencies obtained from the fluorescence data is in full agreement with that from the kinetic method, i.e., CE-ol, CE-in > CE-12 > CE-8 > CE-18 > CE-0. The coaggregating tendencies of the culprits of arteriosclerosis, the cholesteryl esters (CE-n's), have been investigated in the 40:60 V/V (Φ= 0.40) dioxane (DX)-H2O system, by using decyl pyrenyl ketone (Py-11) as the fluorescence probe. The fluorescence intensity of Py-11 decreases when coaggregation occurs between CE-n and Py-11, because of the low polarity of the microenviroment of the coaggregates. The order of the coaggregating tendencies obtained from the fluorescence data is in full agreement with that from the kinetic method, i.e., CE-ol, CE-in > CE-12 > CE-8 > CE-18 > CE-0.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 1994年第3期277-282,共6页 中国化学(英文版)
基金 Project supported by the National Natural Science Foundation of China.
关键词 Cholesteryl esters fluorescence probe coaggregating tendency. Cholesteryl esters, fluorescence probe, coaggregating tendency.
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