慢性肾衰患者血液透析前后血浆皮质醇水平变化及其临床意义

The Clinic Meaning ofthe Level Change of Plasma HydrocortisoneBefore or After Hemodialysis in the Patients withChronic Renal Failure

本文测定了２１例慢性肾功能衰竭（ＣＲＦ）患者血液透析（ＨＤ）前后及透析器动静脉端血浆皮质醇（Ｆ）。发现ＨＤ前血浆Ｆ非常显著地高于正常对照组（ｔ＝３．７０９，Ｐ＜０．００１）；透析器静脉端血浆Ｆ低于动脉端，但缺乏统计学意义（ｔ＝１．５８２，Ｐ＞０．０５）；ＨＤ４小时后的结果高于ＨＤ前，两者比较无显著性差异（ｔ＝０．５９１，Ｐ＞０．０５）。提示ＨＤ对血浆Ｆ无清除作用。

Abstract The authors detected plasma hydrocortisone (F) in artery and vein termination of the dialyser before or after hemodialysis (HD) in 21 patients with chronicrenal falure. The result showed: plasma hydrocortisone was higher notably than thatthe normal contrast group (t= 3. 709, P<0. 001 ) berore HD ; plasma F in vein termination of the dialyser was lower than that which in artery termination of the dialyser, butit was not significance in statistics (t= 1. 582, P>0. 05). After 4 hours HD, the valueof plasma F was higher than that the value of before HD, which were not difference notably in the both. (t=0. 591, P>0. 05). This suggests: HD has not clean function forplasma F.