四种常见胶原病流变性改变及分析

HEMORHEOLOGICAL CHANGES AND ANALYSIS OF FOUR COLLAGEN DISEASES

本文报导了４３例自身见疫性胶原病的血液流变学改变．发现１５例（３４．８８％）ηｂ升高，１１例（２５．５８％）ηｐ升高，而低切变率ηｂ降低的２１例（４８．８３％）．ηｐ降低者２例。对流变学主要改变的成因和意义进行了分析讨论，认为自身抗体的产生是引起红细胞聚集进而引起ηｂ、ηｐ升高的主要原因，而引起ηｂ降低的因素中ＨＣＴ尤应注意，并认为锥板式粘度计测量ηｐ有缺隐及用ＴＫ值评估本类患者红细胞变形能力应持谨慎态度．

The hemorheological changes were reported in 43 patients with auto immune collagen diseases (PSS 23, PA 9,SLE 8,RA 3 cases). It was found that in 15 cases (34. 88%)ηb, and in 11 cases (25. 58%)ηp were increased while 21 cases (48.83%) ηb were lowered than that of normal in shear rate 5. 75s-1 The significance and causes of hemorheological changes were discussed. Considered that the autoantibodies were main causes for the aggregation of RBC's further ηb ηp increasing. The lowered HCT was very significant leading to the ηb and ηp decreasing. And it was not a suitable instrument for measuring ηp by cone-plate viscosimeter.