新生儿硬肿症血液流变特性及其意义的研究

STUDY ON HEMORHEOLOGICAL CHARACTERISTICS AND ITS SIGNIFICANCE OF SCLEREDEMA NEONATORUM

新生儿硬肿症是由受寒、早产、感染、室息等多种原因引起的皮肤和皮下脂肪硬化与水肿的一种疾病．国内自70年代早期开始对新生儿低体温和硬肿症的病理生理与治．做了大量的研究工作、使其病死率有所降低，但迄今其仍为威胁新生儿健康和生命的严重疾病之一。本文研究目的在于阐述血液流变特性异常是新生儿疗硬肿症发病机理之一．为采用血液流变学治疗方法提供理论参考。

Hemorheological parameters, blood lipids, fibrinogen concentration of blood, hematocrit, erythrocyte and hemoglobin count were studied in 8 patients with scleredema neonates(DS group )as compared with 11 healthy neonates(NS group). The resuts show that the yield stress(τ0), aggregation index of red blood (RAT) and relative blood viscosity (ηr,) in DS group are higher than those in NS group (p < 0. 05). It suggested that abnormal hemorheology be associated with pathogenesis of scleredema neonatorum.