摘要
本研究观察大黄灵脾汤对慢性肾衰的免疫调节作用,以论证大黄灵脾汤治疗慢性肾衰的疗效,并探讨其部份机理。34例慢性肾衰治疗前后的 OKT 值比较有显著性差异,T_4/T_8比值 P<0.001。结果提示:大黄灵脾汤对各期慢性肾衰的病程进展有不同程度的延缓作用,能有效地提高细胞免疫调节功能及有效地控制或改善临床症状。
It is considered that T cell immunoregulation play a chief role in the pathogenesis of uremic syndrome.The effect of Rheum-Epimedium Decoction(RED)on T cell immunoregulation of chronic renal failure(CRF)was observed.T lymphocyte subset was studied with monoclonal antibody in 34 CRF patients.The result showed that the ratio of T_4/T_8 decreased significantly.After 3 months of RED therapy,there was significant change of the OKT level in CRF patients,the ratio of T4/T8 increased and near the normal level(P<0.001).It is assumed that:(1)RED could retard the progress of CRF.(2)RED might significantly enhance the T cell immunity,control or improve the clinical syndromes.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1994年第S1期52-54,422,共4页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
大黄灵脾汤
慢性肾功能衰竭
T
淋巴细胞亚群
尿毒症抑制物
Rheum-Epimedium Decoction
T lymphocyte subset
chronic renal failure
production of ureraic inhibitors
