血浆儿茶酚胺含量与老年高血压患者室性心律失常的关系

Relationship between Plasma Catecholamines and Ventricular Arrhythmias in Senile Patients with Essential Hypertension

观察老年期与老年前期高血压患者心律失常的发生及与血浆儿茶酚胺（CA）含量的关系。结果表明，老年期高血压患者室性心律失常的发生率较老年前期显著增多；血浆去甲肾上腺素（NE）、肾上腺素（E）含量较老年前期显著增高；血浆NE含量与24h室性早搏（VPC）总数显著正相关（r=0.356，P＜0.01）。经卡托普利治疗后，血浆NE，E含量均显著下降．室性心律失常的发生率显著降低。本文提示，交感─肾上腺素系统活性增强是引起老年高血压患者室性心律失常的重要因素。

The incidence of arrhythmias and its relation to plas-ma catecholamines (CA) in senile and presenile Patients with essentialhypertention (EH) were studied. The results showed that ventriculararrhythmia was incred significantly in the senile petients than thatin the presenile and the contents of plasina norepinephrine (NE),epinephrine (E) were significantly highcr in the senile patiens as well.In the former, plasma NE was peitively correlated with 24 hour ven-tricular premature contractions (VPC) (r= 0. 356, P< 0. 01). Thecontents of NE, E and incidence of ventricular arrhythmias were de-Creased significantly after treatment of captopril. The results indicatethat hyperactivity of sympethoadrenal system may be an importantfactor to induce ventricu1ar arrhythmias in the senile petients with es-sential hypertension.