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尿激酶静脉溶栓治疗老年人急性心肌梗塞 被引量:2

INTRAVENOUS UROKINASE IN ELDERLY PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
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摘要 The asults of forty-twe pabents witll AMI(≥60 yeas 26 cases) treated with intravenous urokinasc(Group A) were reported. Another 168 patientswith AMI wthout urokinase administration in thesame period (Group B) were selectcd for compari-son. The coronary artery recanalization rate ofGroup A paticnts were 61.9% with no significantdifferencc between those aged ≤60 years and≥60 yeas (P>0.05). The hospitalization mor-tality was significantly lowcr in Group A (4.8%)than in Group B(22.6%, P<0.001). In paticntsaged ≥60 years, the hospitalization mortality wilssigniticantly lower in Grolip A (7.7%) than inGroup B too(27.1 %, P<0.01). Four Group A pa-tients complicateed with mild haemorrhage andtwo with hypotention. The effcctiveness and safetyor thrombolytic therapy in eldly patients withAMI were discussed. The asults of forty-twe pabents witll AMI(≥60 yeas 26 cases) treated with intravenous urokinasc(Group A) were reported. Another 168 patientswith AMI wthout urokinase administration in thesame period (Group B) were selectcd for compari-son. The coronary artery recanalization rate ofGroup A paticnts were 61.9% with no significantdifferencc between those aged ≤60 years and≥60 yeas (P>0.05). The hospitalization mor-tality was significantly lowcr in Group A (4.8%)than in Group B(22.6%, P<0.001). In paticntsaged ≥60 years, the hospitalization mortality wilssigniticantly lower in Grolip A (7.7%) than inGroup B too(27.1 %, P<0.01). Four Group A pa-tients complicateed with mild haemorrhage andtwo with hypotention. The effcctiveness and safetyor thrombolytic therapy in eldly patients withAMI were discussed.
出处 《广东医学》 CAS CSCD 1994年第7期436-437,504,共3页 Guangdong Medical Journal
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  • 1钱小明,林修功.溶栓、抗凝、抗血小板在急性心肌梗死中的配伍应用[J].国外医学(老年医学分册),1993,14(6):244-246. 被引量:1
  • 2(Collaborative Research Group. Fu Wai Hospital,CAMS, Bei jing 100037).急性心肌梗塞溶栓治疗对比研究[J].中华心血管病杂志,1994,22(1):17-19. 被引量:140
  • 3PasedNicodetJ.Thechallengeoffurtherreducingcardiacmortalityinthethrornbolvticera. Circulation . 1993
  • 4ACC/AHA guidelimes for the early managernent ofpatientswithacutemyocardialinlarction. Circdation . 1990
  • 5Gruppo Italianoper10 StudiodellastreplochinasinellInfartoMiocardico[GISSI]:Effectivenssofintravenousthromblytictreatmentinacutemyocardialinfarction. The Lancet . 1986
  • 6DC.Gnlba,G,Clans.THlombolysetherapledesHerginfarht德国医学,1993.
  • 7ISIS[SecondInternationalStudyofInfarctSurvial]CollabrativeGroup.Randomizedtrialofintravenousstleptokinase,Oralaspirin,bothorneitheramong17,187casesofsuspectdacutemyocardialinfaction:ISIS-2. The Lancet . 1988
  • 8SolSherrg,,J,Marder.Mistakenguidelinesforthromblytictherapgyofacutemyocardialinfarctionintheelderl. Journalism Assn of Community College . 1991

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