摘要
自制纤溶酶,用发色底物法测定人血浆α_2-AP活性:24例正常人血浆α_2-AP活性为97.2±13.3;肝癌、肝硬化、白血病、DIC病人的α_2-AP活性较正常组显著减低;心肌梗塞、血栓性静脉炎的α_2-AP活性显著增高;而正常孕妇的α_2-AP活性与正常人无显著差异。同时监测了1例用尿激酶作溶栓治疗的心肌梗塞病人的α_2-AP活性并对结果进行了讨论。
A method for assaying α2-antiplasmin in human plasma by chromogenic tripeptide substrate S-2251 was estabolished. The results showed that the α2-antiplasmin activity in 24 normals was 97. 2±13. 3%. The α2-antiplasmin activity was decreased in hepatic carcinoma, cirhosis, leukemia and DIC etc, but elevated in myocardia and thromboangitis. It was normal in preganancy women. The detection of antiplasmin activity in thrombolytic therapy of acute myocardial infarction might be helpful for observation of therapeutic effect and might eveluate the prognosis.
出处
《血栓与止血学》
1994年第4期152-153,190,共3页
Chinese Journal of Thrombosis and Hemostasis
