摘要
In this study platelet 3H-paroxetine binding site was studied in 16 depressed pa-tients and 16 healthy volunteers. We found that the mean Bmax of 3H-paroxetine binding on theplatelets of depressed patients was significantly lower than that of normal controls. After treated withamitriptyline or electro-acupuncture for 6 weeks, the density of paroxetine binding sites increased to-wards normal in well responded patients. But no significant difference was found between electro-acupuncture and amitriptyline as compared in their effects on 3H-paroxetine binding sites.
In this study platelet 3H-paroxetine binding site was studied in 16 depressed pa- tients and 16 healthy volunteers. We found that the mean Bmax of 3H-paroxetine binding on the platelets of depressed patients was significantly lower than that of normal controls. After treated with amitriptyline or electro-acupuncture for 6 weeks, the density of paroxetine binding sites increased to- wards normal in well responded patients. But no significant difference was found between electro- acupuncture and amitriptyline as compared in their effects on 3H-paroxetine binding sites.
