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Study on Cellular Differentiation and Genes Rearrangement of Malignant Lymphoproliferative Disorders 被引量:1

Study on Cellular Differentiation and Genes Rearrangement of Malignant Lymphoproliferative Disorders
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摘要 Malignant lymphoproliferative disorders are common diseases characterized by the clonal proliferation of cells derived from the lymphocytes of different developmental stages. The analyses of routine morphology and cytochemistry fail to determine the origin and differentiation stages. The cell differentiation origin of most of malignant lymphoproliferative disorders can be defined by using monoclonal antibodies(McAbs) against the differentiation antigens of lymphocytes, but it is unable to determine the cell origin of a minority of undifferentiated malignancies and also fails to distinguish the malig-
出处 《Chinese Science Bulletin》 SCIE EI CAS 1993年第21期1833-1837,共5页
基金 Project supported by the Commission of Science and Technology of Shandong Province.
关键词 MALIGNANT LYMPHOPROLIFERATIVE disorders differentiation ANTIGENS polymerase chain reaction IMMUNOGLOBULIN GENE REARRANGEMENT T-cell receptors GENE REARRANGEMENT MALIGNANT LYMPHOPROLIFERATIVE DISORDERS DIFFERENTIATION ANTIGENS POLYMERASE CHAIN REACTION IMMUNOGLOBULIN GENE REARRANGEMENT T-CELL RECEPTORS GENE REARRANGEMENT
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  • 1Madisen L.DNA banking: the effects of storage of blood and isolated DNA on the integrity of DNA. American Journal of Medical Genetics . 1987
  • 2Cossman J,Zehnbauer B,Garrett CT,et al.Gene rearrangements in the diagnosis of lymphoma/leukemia. American Journal of Clinical Pathology . 1991
  • 3Griesser H,Tkachrk D,Reis MD,et al.Gene rearrangement and translocations in lymphopro liferative diseases. Blood . 1989
  • 4Griesinger F,Greenberg JM,Kersey JH.T cell receptor gamma and delta rearrangement in hematologic malignancies. The Journal of Clinical Investigation . 1989
  • 5朱平,宗建超,刘福森,刘乐宇,殷慧君.淋巴恶性肿瘤的免疫球蛋白基因重排[J].科学通报,1991,36(19):1506-1509. 被引量:7

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