摘要
It was investigated that the localization and distribution of calcitonin gene-relatedpeptide (CGRP) in the rabbit lung by ABC-GDN immunohistochemistry.The results demon-strated that CGRP immunoreactivity was located in neuroendocrine cells (NEC_s) and neu-roepthelial bodies (NEB_s),including all airways from bronchi,bronchioles,and alveolar ducts.The nerve fibers in walls of the intrapulmonary bronchi and blood vessels also had CGRP-immunoreactivity.Adjacent sections immunostained with antibodies to CGRP and 5-HT provedthe coexistence of CGRP and 5-HT in NECs and NEBs.This finding suggested the possibilityof functional interaction between the peptide and amine.
It was investigated that the localization and distribution of calcitonin gene-related peptide (CGRP) in the rabbit lung by ABC-GDN immunohistochemistry.The results demon- strated that CGRP immunoreactivity was located in neuroendocrine cells (NEC_s) and neu- roepthelial bodies (NEB_s),including all airways from bronchi,bronchioles,and alveolar ducts. The nerve fibers in walls of the intrapulmonary bronchi and blood vessels also had CGRP- immunoreactivity.Adjacent sections immunostained with antibodies to CGRP and 5-HT proved the coexistence of CGRP and 5-HT in NECs and NEBs.This finding suggested the possibility of functional interaction between the peptide and amine.
