摘要
To evaluate the diagnostic value of the abnormal systolic blood pressure (SBP) re-covery ratio of exercise test and its mechanisms,142 patients with suspectable angina pectorisunderwent coronary angiography and treadmill exercise test.The SBP recovery ratios at the1st,3rd,and 6th min of the recovery period in patients with coronary artery disease (CAD)were significant higher than those in the control subjects.Of the hymodynamic variables,car-diac index (CI),stroke volume index (SI) and ejection fraction (EF) were lower,left ventricu-lar end-diastolic pressure (LVEDP) and systemic vascular resistance (SVR) were higher in pa-tients with abnormal SBP response than in patients with normal SBP response.The sensitivityof abnormal SBP recovery ratio for identifying patients with CAD was 68% and the specificitywas 90%.The false positivity rate of abnormal SBP recovery ratios in 21 patients with hyper-tension without CAD was 38%.These results indicate that an abnormal SBP recovery ratio is auseful index for identifying patients with CAD.When the ST segment response to exercise isnormal or borderline,it can increase the sensitivity and the accuracy of the exercise test.Theabnormal SBP response appears to be due to exercise-induced impairment of left ventricularfunction and increase in systemic vascular resistance.
To evaluate the diagnostic value of the abnormal systolic blood pressure (SBP) re- covery ratio of exercise test and its mechanisms,142 patients with suspectable angina pectoris underwent coronary angiography and treadmill exercise test.The SBP recovery ratios at the 1st,3rd,and 6th min of the recovery period in patients with coronary artery disease (CAD) were significant higher than those in the control subjects.Of the hymodynamic variables,car- diac index (CI),stroke volume index (SI) and ejection fraction (EF) were lower,left ventricu- lar end-diastolic pressure (LVEDP) and systemic vascular resistance (SVR) were higher in pa- tients with abnormal SBP response than in patients with normal SBP response.The sensitivity of abnormal SBP recovery ratio for identifying patients with CAD was 68% and the specificity was 90%.The false positivity rate of abnormal SBP recovery ratios in 21 patients with hyper- tension without CAD was 38%.These results indicate that an abnormal SBP recovery ratio is a useful index for identifying patients with CAD.When the ST segment response to exercise is normal or borderline,it can increase the sensitivity and the accuracy of the exercise test.The abnormal SBP response appears to be due to exercise-induced impairment of left ventricular function and increase in systemic vascular resistance.