摘要
Chromosomes in 1620 metaphases of ascitic fluid cells in 20 cases of ovariancarcinoma were analyzed.The results showed that there were marked structuralaberrations aside from significant increase in chromosomal numerical aberrations(85.2%).In the ascitic fluid cells from 12 patients,15 types of marker chromosomes were found,among which t(6;14)(q21;q24)and t(2;6)(q35;p12)were more frequently noted witha rate of 7.84% and 7.59% respectively,which was significantly higher than that of othermarker chromosomes(P【0.01).The findings suggested that,besides t(6;14)(q21;q24),t(2;6)(q35;p12)may also be a specific marker chromosome of ovarian carcinoma.
Chromosomes in 1620 metaphases of ascitic fluid cells in 20 cases of ovarian carcinoma were analyzed.The results showed that there were marked structural aberrations aside from significant increase in chromosomal numerical aberrations(85.2%). In the ascitic fluid cells from 12 patients,15 types of marker chromosomes were found, among which t(6;14)(q21;q24)and t(2;6)(q35;p12)were more frequently noted with a rate of 7.84% and 7.59% respectively,which was significantly higher than that of other marker chromosomes(P<0.01).The findings suggested that,besides t(6;14)(q21;q24), t(2;6)(q35;p12)may also be a specific marker chromosome of ovarian carcinoma.
