一阶导数光谱法测定茵栀黄注射液中黄芩甙的含量

Determination of Content of Baiealin in Injection of Herba Artemisiae Capillaris, Capeiasmine and Radix Scutellarlac

茵栀黄注射液是由黄芩、茵陈、栀子和银花组成,临床上用于治疗急、慢性病毒肝炎,疗效确切。上海药品标准(沪Q/WS—1—953—80)以测黄芩甙含量为注射液的质量指标。由于茵栀黄为复方制剂,其余成份在紫外区也有吸收,从而干扰黄芩甙的测定。为此,本实验采用一阶导数光谱法,不经分离,有效地排除了干扰,对黄芩甙的测定取得了满意的结果。

This paper reports direct determination of the content of baicalin in injection of Herba Artemisiae Capillaris, Capejasmine and Radix Scutellariae, using a 751-GW spectrophotometer proctuced in China. The correlation coefficient of the standard curve γ=0.99992. The average recovery was 99.79±1.12%. CV=1.06%.