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冠心病家族史在冠心病发病中作用地位的研究 被引量:3

A STUDY ON ROLE OF FAMILY HISTORY IN DEVELOPMENT OF CORONARY HEART DISEASE
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摘要 108例经冠状动脉造影检查(CAG)确诊为冠心病和45例CAG检查结果正常的病人进行了冠心病危险因素的病例对照研究.发现冠心病家族史、高血压病家族史、吸烟、高脂饮食习惯和年龄是冠心病的主要危险因素,其中冠心病家族史的优势比(OR)为5.82,占诸危险因素的首位.冠心病、高血压和脑卒中家族史合并出现时,冠心病的OR值显著提高.多因素分析和分层分析均提示,冠心病家族史是一个独立的危险因素. A case - control study with 108 cases of coronary heart disease (CHD) and 45 non - CHD controls identified by coronary an-giography was conducted. It was found that family history of CHD,family history of hypertension,cigarette smoking,high intake of animal fat and age were major risk factors for CHD. Among them, odds ratio (OR) of CHD family history was the highest. Individuals with a family history of two or more cardiovascular diseases (CHD,hypertension and stroke),they had a significantly increased OR. An analysis with multiple logistic regression and Mantel-Haenzel method showed that family history of CHD was an independent risk factor for CHD.
出处 《中国慢性病预防与控制》 CAS 1993年第4期158-160,192,共4页 Chinese Journal of Prevention and Control of Chronic Diseases
关键词 冠心病 家族史 危险因素 冠状动脉造影 Coronary heart disease Family history Risk factors Coronary angiograghy
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