化脓性中耳炎血清及耳分泌物总IgE的测定

Test for Total IgE in Suppurative Otitis Media

本文通过16例急性化脓性中耳炎(急性组),28例间歇性发作慢性化脓性中耳炎(间歇性发作流脓组)及42例慢性化脓性中耳炎长期流脓(长期流脓组)患者血清及耳分泌物的总IgE进行检测。测定分泌物中总IgE几何平均值±标准差,急性组为7.65±5.1iu/ml,间歇性发作流脓组为9.89±6.3iu/ml及长期流脓组为41.12±18.56iu/ml。长期流脓组分泌物中的总IgE明显高于其它两组(P<0.01),而三组血清的IgE无明显差异。本结果表明中耳局部存在IgE,并提示慢性化脓性中耳炎长期流脓与变态反应有关。

Total IgE in both serum and secretion of 16 cases with acute suppurative otitis media (ASOM),28 cases with occasionally active chronic suppurative otitis media (OACSOM) and 42 cases with frequently active chronic suppurative otitis media (FASOM) was quantitativaly measured by using PRIST (paper radioimmunosorbent test). The geometric mean±standard devation for total secretory IgE was significntly greater in FACSOM (41.12±18.56 iu/ml)than those in either ASOM(7.65±5.12 iu/ml) or FACSOM (9.89±6.32 iu/ml)(P<0.01). That was not true for total IgE in the serum. Our data cofirmed that 1. There are IgE in the middle ear. 2. FACSOM always was associated with allergy.