高原肺心病急性发作期286例临床特点分析

CLINICAL FEATURE IN ACUTE STAGE OF CHRONIC COR PULMONALE AT HIGH ALTITUDE: A STUDIES OF 286 CASES

本文对高原地区(海拔2260～3200m)286例慢性肺心病急性发作期病人作了临床特点分析。结果表明:①PaO_2和PaCO_2(分别为5.38±0.98和6.20±1.09kPa)均明显低于平原肺心病;②肺性脑病并发率(3.8％)较平原低;③血液粘度较平原高,高粘血症组呼衰、右心衰和肾功异常的发生率(分别为94.5、84.6、29.2％)明显高于血粘度正常组(分别为52.3、45.2、14.2％)。对其机理和临床意义进行了讨论。

The authors studied the clinical feature in 286 cases with acute stage of high altitude chronic cor pulmonale (HACCP)at 2 260 to 3 200m abve sea level. The results demonstrated that: ①mean PaO_2 ang PaCO_2 in HACCP(5.384±0.98 and 6.204±1.09kPa,respeetively)were lower than those at plain erea chronic cot puimonale(PECCP). ②Pulmonary encephalopathic incidence in HACCP (3.8%)was lower than that in PECCP. ③Blood viscosity in HACCP was higher than that in PECCP. Incidence rate of respiratory failure, right heart failure and impairment of renal function in elevated blood viscosity group(94.5、84.6、29.2%, respectively)were significantly higher than those in normal blood viscosity group(52.3、45.2、14.2% ,respectively),p<0.01.