摘要
本文应用琼脂凝胶双扩散试验检测旋毛虫实验感染的家兔及大白鼠血清,抗体阳性率分别为100%(8/8)和84.62%(11/13),检测旋毛虫病人血清45份,抗体阳性率为91.11%(41/45),且与丝虫、肝吸虫、囊虫及正常人血清均无交叉反应.只有1例肺吸虫病人呈现假阳性反应。此外,旋毛虫病人经丙硫咪唑治疗后可提高旋毛虫抗体的检出率。该试验诊断旋毛虫病具有较高的敏感性和特异性,方法简便,可在基层单位应用。
This paper reports that the agar gel double diffusion test using soluble antigens of the larvaes of trichinella spiralis was used to detect the specific antibodies in the sera of rabbits and rats ex- perimentally infected by trichinella spiralis,with the antibody positive rates 100%(8/8)and 84.62% (11/13),respectively.The 45 sera of patients with trichinosis were detected,the antibody positive rate was 91.11%(41/45).when detecting the sera from patients with filariasis.chonorchiasis,cysticercosis and from normal persons,there were no cross reactions.Only one patient with paragonimiasis showed false positive reaction.In addition,the detective rate of specific antibodies in the sera of patients with trichinosis can be incressed after treatment with albendazole.This test is a higher sensetive,specific and simple method,can be applied to rural areas.
出处
《河南医学研究》
CAS
1993年第2期138-140,共3页
Henan Medical Research
基金
本研究为卫生部青年科学基金及河南省医学科学院基金资助课题的一部分
关键词
旋毛虫病
免疫诊断
琼脂凝胶双扩散试验
抗旋毛虫抗体
交叉反应
trichinosis
immunodiagnosis
agar gel double diffusion test
anti-trichinae antibodies
cross reaction
