摘要
Changes in erythrocyte membrane ATPases and plasma lipid peroxides（LPO） were studiedperioperatively in 15 abdominal surgical patients under intravenous procaine-balanced anesthesia.The resultsrevealed that erythrocyte membrne Na<sup>+</sup>-K<sup>+</sup>ATPase,Mg<sup>2+</sup>ATPase and Ca<sup>2+</sup>-Mg<sup>2+</sup>ATPase activities werenot significantly changed at 60～90 min after incision as compared with 30 min before anesthesia,but weredecreased markedly at 10 rain and 24 hours after completion of operation（P【0.01）.Plasma LPO wereincreased significantly by 24 hours after surgery（P【0.01） following an initially marked but transientreduction.Plasma LPO changes were not correlated with erythrocyte membrane ATPase activities,r=-0.0396,-0.0097 and-0.4383 respeetively（P】0.05）.These correlations are suggested to be inducedby neuroendoerine responses after anesthesia and/or surgical trauma.
Changes in erythrocyte membrane ATPases and plasma lipid peroxides(LPO) were studied perioperatively in 15 abdominal surgical patients under intravenous procaine-balanced anesthesia.The results revealed that erythrocyte membrne Na^+-K^+ATPase,Mg^(2+)ATPase and Ca^(2+)-Mg^(2+)ATPase activities were not significantly changed at 60～90 min after incision as compared with 30 min before anesthesia,but were decreased markedly at 10 rain and 24 hours after completion of operation(P<0.01).Plasma LPO were increased significantly by 24 hours after surgery(P<0.01) following an initially marked but transient reduction.Plasma LPO changes were not correlated with erythrocyte membrane ATPase activities,r= -0.0396,-0.0097 and-0.4383 respeetively(P>0.05).These correlations are suggested to be induced by neuroendoerine responses after anesthesia and/or surgical trauma.
出处
《医学研究生学报》
CAS
1993年第S1期50-54,共5页
Journal of Medical Postgraduates
