268例慢性乙型肝炎患者血清抗-HBc-IgM检测结果分析

Anti-HBc-IgM serum tests among 268 patients with chronic hepatitis B

对268例慢性乙型肝炎患者血清抗-HBc-IgM检测结果,慢性活动性肝炎152例,阳性118例,阳性率77.6%;慢性迁延性肝炎116例,阳性65例,阳性率56.0%。慢性活动性肝炎组明显高于慢性迁延性肝炎组,P<0.01、HBeAg阳性组抗-HBcIgM的阳性率明显高于阴性组。无肝炎病史者172例,抗-HBc-IgM阳性114例,阳性率为66.2%,与有肝炎病史者无明显差别。说明检测血清抗-HBc-IgM对乙型肝炎的诊断及判断其严重程度有着较大的临床价值。

Anti-HBc-IgM serum tests were completed for 268 patients with chronic hepatitis B among whom 118 (77.6%) seropositive persons of 152 patients with chronic active hepatitis (CAH), 65(56%) seropositive persons of 116 patients with chronic persisting hepatitis (CPH) were identified respectively. The seropositive rate in CAH group was evidently higher than that in CPH group (P<0.01). Among the other 172 patients without hepatitis history, 114 (66%) seropositive persons were identified. There was no distinctive difference be- tween those with hepatitis history and those without hepatitis history. The re- sults show that anti-HBc-IgM tests are of great clinical value to the diagnosis of hepatitis B and the evaluation of its severity degree.