117例颌面骨骨纤维异常增殖症的诊断分析

Fibrous dysplasia of jaw and facial bones: A combined anlysis of clinic , radiologic and histopathologic diagnosis of 117 cases

本文对117例颌面骨骨纤维异常增殖症(FD)的诊断作了临床、X线、病理三结合分析,结果显示单骨性占87.2％,多骨性12.8％。X线改变以延伸性生长、边界不清、牙受累轻为特征,并可分为毛玻璃样、囊样、结节硬化和混合型等4型。组织学上由编织骨、板层骨和类圆形骨小体等多种类型构成,纤维性间质中含有丰富的BMP。作者提出颌面骨FD必须采用临床、X线、病理三者的密切结合才能确切诊断。

A clinical-radiologic-histopathologic review of 106 cases of fibrous dysplasia involving the jaws is presented. Ninety eight patients onset in the frist and second decades. Fifteen cases were polyostotic and the remaining cases were monostotic. Radiologi-caly, the lesions showed and extending growth pattern, poor definite border and slight involvement of teeth. The radiographic features were classified into four types: ground grass (52. 0%), sclerotic (8. 0%), cystic-like (8. 0%) and mixed type (32. 0%). Histologically.the lesions were charac- terized by a cellular fibrous stroma that contain varying amounts of mineralized substance, represented by woven bone (63. 0%), lamellar bone (30. 0%) and cementum-like structure (7. 0%). The final definitive diagnosis requires the combined evaluation of clinic, radiologic and histopathologic findings.