40例口底恶性肿瘤的临床治疗分析

Clinical Analysis of 40 cases of maligant tumor of the floor of the mouth

40例口底恶性肿瘤中鳞癌占62.5％,腺样囊性癌占22.5％,为口底恶性肿瘤的两种主要病理类型.治疗方法为同侧颌颈联合根治术,选择性作对侧舌骨上颈清和功能性颈清.65％的病人作了术前化疗.Ⅲ-Ⅳ期病人占全组的72.5％,总5年生存串达50％。I～Ⅲ期5年生存率达78.6％.病理类型较差或分化程度较差者虽经术前化疗,其5年生存率、复发率和死亡率均与单纯手术组无明显差别.即使化疗有效,其5年生存串与化疗无效者相比亦无统计学差别。晚期病人的生存率,鳞癌比腺样囊性癌高.

This is a retrospective review for 40 patients with malignant tumour of the floor of mouth . In the group, squamous carcinoma is 62. 5%. adenoid cystic carcinoma is 22- 5%. Both of them are the major type .stageⅢ.Ⅳ were 72-5%, Generally ipsilateral; radical mandibular and neck dissection was performed selectively. 65% of patient were given preoprative chemotherapy. Total 5 years survival rate was 50%,for stage Ⅰ -Ⅲwere 78. 6%. Although preoperative chemotherapy was given that the group of lower pathological differetiation was still in lower survival rate, higher recurrency and mortality than those given surgery alone. Survival rate for squamous carcinoma was higher than that for adenoid cystic carcinoma.