肝癌碘油化疗性栓塞术——疗效及影响因素分析

Iodized Oil Chemoembolization of Primary Liver Caneer(Curative Effect and Influential Factors Evaluation)

肝动脉碘油化疗性栓塞术(下称LP-TAE术)是目前治疗中晚期原发性肝癌最有效的姑息疗法之一。本文对52例原发性肝癌经LP-TAE术治疗后的42例随访资料作了较全面、系统的疗效评估及疗效影响因素分析。结果显示术后中位生存期11.5个月,半年、1年和2年生存率分别为70％、56.8％和42.5％;影响疗效的主要因素为肿瘤大小、肿瘤有无包膜、门脉主干有无癌栓及施行LP-TAE术的次数。

Hepatic artery chemoembolization with iodized oil suspension mixed with anticancer agents (LP—TAE) was one of the most effective palliative therapies for unresectable primary liver cancer at present. In an attempt to evaluate its curative effect and influential factors, we made this study with comprehensive and systematic stastistical methods in 52 cases with unresectable primary liver cancer. The results revealed that (1) median survival time was 11.5 months; sixmonth,one—year and two-year survival rate were 70%, 56.8% and 49.5% respectively after LP—TAE. (2) the main influential factors of LPTAE was tumor size, tumor capsule (encapsulated or unencapsulated), tumor embolus of main portal vein (with or without) and LP-TAE frequency.