影响慢重肝及其并发症转归的因素——附98例临床分析

Dynamical Observation on HBV-induced Change of Tumour Necrosis Factor in Vitro

报告98例慢重肝与并发症的转归,证明与并发症的性质、多少密切相关,早期应用肝细胞生长素可降低病死率。

The dynamical observation on HBV-induced changes of Tumour Necrosis Factor (TNF) in myeloid cells were carried out.The results showed that the level of TNF in HBV infected myeloid cell group was higher than that of the normal control in any period,especially in the periods of 72 hours and 1 week after inoculating HBV (P<0.01).The levels of TNF in HBV infected myeloneutrophil group,myelolymphocyte group and myelomonocyte group were higher than those of the normal controls.These results suggested TNF may be induced by HBV in myeloid cell and TNF may be involved in the pathological effect of HBV on myeloid cell.