The Reaction of ∝, β-epoxyketones with methoxymethylenetriphenylphosphorane, A New Approach to ∝-alkylsubstituted-γ-hydroxy-d, β-unsaturated aldehydes
The Reaction of ∝, β-epoxyketones with methoxymethylenetriphenylphosphorane, A New Approach to ∝-alkylsubstituted-γ-hydroxy-d, β-unsaturated aldehydes
摘要
The reaction of α, β-epoxyketones with methoxymethylenetriphenyl- phosphorane provides a method for the preparation of α-alkylsubstituted γ-hydroxy-α, β-unsaturated aldehydes with one carbon homologation and retention of configuration.
The reaction of α, β-epoxyketones with methoxymethylenetriphenyl- phosphorane provides a method for the preparation of α-alkylsubstituted γ-hydroxy-α, β-unsaturated aldehydes with one carbon homologation and retention of configuration.
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1Ding, WY,Cao, WG,Yao, Y,Zhu, ZM.Synthesis of dimethyl 3-perfluoroalkyl-4-(3-oxo-2-triphenyl-phosphoranylidenbutanylidene)-pent-2-enedioate and its cyclization[J].Chinese Journal of Chemistry,1995,13(5):468-474.
-
2ZHANG ShiLei,XIE HeXin,SONG AiGuo,WU DeYan,ZHU Jin,ZHAO SiHan,LI Jian,YU XinHong,WANG Wei.Efficient preparation of trans-α,β-unsaturated aldehydes from saturated aldehydes by oxidative enamine catalysis[J].Science China Chemistry,2011,54(12):1932-1936.
-
3Wen Qiang Du,Ze Ming Rong,Yan Liang,Yong Wang,Xin Yi Lu,Yi Fan Wang,Lian Hai Lu.Chemoselective hydrogenation of α,β-unsaturated aldehydes with modified Pd/C catalyst[J].Chinese Chemical Letters,2012,23(7):773-776. 被引量：1
-
4马正月,张兴华,王士奎,何洋,杨更亮,李蓓蕾,杨俊杰,鲁悦娟,孙杰威.Design and Synthesis of α, β-Epoxyketones as New Anticancer Agents[J].Chinese Journal of Chemistry,2011,29(4):757-764. 被引量：3
-
5Wei LU,Guang Rong ZHENG,A. A.HAJI,Jun Chao CAI(Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031).Synthesis of 3(R)-(t-Butyldiphenylsilyloxy)-1-penten-4-yne, via an Improved Procedure for Aldehyde-to-Alkyne Homologation[J].Chinese Chemical Letters,1998,9(7):621-623.
-
6肖贻崧,王彦广.Synthesis of Substituted Pyrroles via Ultrasound Assisted Three-component Coupling Reaction of Amines, α,β-Unsaturated Aldehydes and Nitroalkanes[J].Chinese Journal of Chemistry,2003,21(5):562-565.
-
7LI Hao1,JI YaFei2,LI Jian2,ZHANG ShiLei1,YU ChenGuang1 & WANG Wei1,2 1 Department of Chemistry and Chemical Biology,University of New Mexico,Albuquerque,NM 87131-0001,USA,2 Department of Pharmaceutical Sciences,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China.Organocatalytic enantioselective Michael addition reactions of fluoromalonates with α,β-unsaturated aldehydes[J].Science China Chemistry,2010,53(1):135-139.
-
8Guang Yan HUANG,Yu GUO,Xiao Tian LIANG(Institute of Materia Medica. Chiners Academy of Medical Sciencs &Peking Union Medical College, Beijing 100050).Homologation of Taxol Side Chain via Arndt－Eistert Reaction Involving the Wolff Rearrangement[J].Chinese Chemical Letters,1996,7(12):1077-1078. 被引量：1
-
9HUANG,Wei-Yuan WU,Yong-Ming Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032.Studies on the reactions of silyl enol ether with perfluoroorganic compounds——Ⅲ.Synthesis of perfluoroalkylated α,β-unsaturated aldehydes and their derivatives[J].Chinese Journal of Chemistry,1992,10(4):373-378.
-
10HU, Chang-Ming CHEN, JianShanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.Study on the stannous halides promoted addition of 1,1,1-trichloro-2,2,2-trifluoroethane to aldehydes and the chemical transformation thereof[J].Chinese Journal of Chemistry,1994,12(2):183-189.
